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A comparison of position-specific score matrices based on sequence and structure alignments

Sequence comparison methods based on position-specific score matrices (PSSMs) have proven a useful tool for recognition of the divergent members of a protein family and for annotation of functional sites. Here we investigate one of the factors that affects overall performance of PSSMs in a PSI-BLAST...

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Autori principali: Panchenko, Anna R., Bryant, Stephen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373449/
https://ncbi.nlm.nih.gov/pubmed/11790846
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