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Contributions of folding cores to the thermostabilities of two ribonucleases H

To investigate the contribution of the folding cores to the thermodynamic stability of RNases H, we used rational design to create two chimeras composed of parts of a thermophilic and a mesophilic RNase H. Each chimera combines the folding core from one parent protein and the remaining parts of the...

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Bibliografiske detaljer
Main Authors: Robic, Srebrenka, Berger, James M., Marqusee, Susan
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373436/
https://ncbi.nlm.nih.gov/pubmed/11790848
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