Pathogenesis of adenovirus type 5 pneumonia in cotton rats (Sigmodon hispidus).

Cotton rats (Sigmodon hispidus) were inoculated intranasally with 10(2.0) to 10(10.0) PFU of human adenovirus type 5. The virus replicated to a high titer in pulmonary tissues, with the peak titer being proportional to the input dose. The 50% lethal dose was 10(9.4) PFU. Histopathologic changes were...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Prince, G A, Porter, D D, Jenson, A B, Horswood, R L, Chanock, R M, Ginsberg, H S
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.1.101-111.1993
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