Pathogenesis of adenovirus type 5 pneumonia in cotton rats (Sigmodon hispidus).

Cotton rats (Sigmodon hispidus) were inoculated intranasally with 10(2.0) to 10(10.0) PFU of human adenovirus type 5. The virus replicated to a high titer in pulmonary tissues, with the peak titer being proportional to the input dose. The 50% lethal dose was 10(9.4) PFU. Histopathologic changes were...

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Bibliografische gegevens
Hoofdauteurs: Prince, G A, Porter, D D, Jenson, A B, Horswood, R L, Chanock, R M, Ginsberg, H S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC237342/
https://ncbi.nlm.nih.gov/pubmed/8380066
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