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Structural basis for NKG2A/CD94 recognition of HLA-E

The NKG2x/CD94 (x = A, C, E) natural killer-cell receptors perform an important role in immunosurveillance by binding to HLA-E complexes that exclusively present peptides derived from MHC class I leader sequences, thereby monitoring MHC class I expression. We have determined the crystal structure of...

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Hlavní autoři: Kaiser, Brett K., Pizarro, Juan Carlos, Kerns, Julie, Strong, Roland K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373352/
https://ncbi.nlm.nih.gov/pubmed/18448674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802736105
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