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Structural basis for NKG2A/CD94 recognition of HLA-E
The NKG2x/CD94 (x = A, C, E) natural killer-cell receptors perform an important role in immunosurveillance by binding to HLA-E complexes that exclusively present peptides derived from MHC class I leader sequences, thereby monitoring MHC class I expression. We have determined the crystal structure of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373352/ https://ncbi.nlm.nih.gov/pubmed/18448674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802736105 |
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