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Activation of FAK and Src are receptor-proximal events required for netrin signaling

The axon guidance cue netrin is importantly involved in neuronal development. DCC (deleted in colorectal cancer) is a functional receptor for netrin and mediates axon outgrowth and the steering response. Here we show that different regions of the intracellular domain of DCC directly interacted with...

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Autores principales: Li, Weiquan, Lee, Jeeyong, Vikis, Haris G, Lee, Seung-Hee, Liu, Guofa, Aurandt, Jennifer, Shen, Tang-Long, Fearon, Eric R, Guan, Jun-Lin, Han, Min, Rao, Yi, Hong, Kyonsoo, Guan, Kun-Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373267/
https://ncbi.nlm.nih.gov/pubmed/15494734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1329
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