DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors.
None of the vector systems currently available for gene therapy applications have been shown to be capable of both efficient gene transfer into nondividing cells and long-term expression through stable integration into host cell DNA. While integrating vectors based on adeno-associated virus are capa...
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| Pubblicato in: | J Virol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1994
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8282-8287.1994 |
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