DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors.

None of the vector systems currently available for gene therapy applications have been shown to be capable of both efficient gene transfer into nondividing cells and long-term expression through stable integration into host cell DNA. While integrating vectors based on adeno-associated virus are capa...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Alexander, I E, Russell, D W, Miller, A D
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8282-8287.1994
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