Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro.

The perivascular location of human immunodeficiency virus-infected cells suggests that the virus enters the central nervous system (CNS) by traversing the blood-brain barrier (BBB). In this study, the simian immunodeficiency virus (SIV) macaque model was used to determine whether SIV infects CNS end...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mankowski, J L, Spelman, J P, Ressetar, H G, Strandberg, J D, Laterra, J, Carter, D L, Clements, J E, Zink, M C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8202-8208.1994
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