Distribution of drug resistance mutations in type 3 poliovirus identifies three regions involved in uncoating functions.

We have previously described the use of an uncoating inhibitor, WIN 51711, to select drug-resistant mutants of the Sabin strain of poliovirus type 3. Two-thirds of the mutants proved to be dependent on the drug for plaque formation because of extreme thermolability (A. G. Mosser and R. R. Rueckert,...

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Pubblicato in:	J Virol
Autori principali:	Mosser, A G, Sgro, J Y, Rueckert, R R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8193-8201.1994
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