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Distribution of drug resistance mutations in type 3 poliovirus identifies three regions involved in uncoating functions.

We have previously described the use of an uncoating inhibitor, WIN 51711, to select drug-resistant mutants of the Sabin strain of poliovirus type 3. Two-thirds of the mutants proved to be dependent on the drug for plaque formation because of extreme thermolability (A. G. Mosser and R. R. Rueckert,...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Mosser, A G, Sgro, J Y, Rueckert, R R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8193-8201.1994
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