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CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection.

In this study, we have examined the relative contributions of CD4+ and CD8+ T cells in controlling an acute or chronic lymphocytic choriomeningitis virus (LCMV) infection. To study acute infection, we used the LCMV Armstrong strain, which is cleared by adult mice in 8 to 10 days, and to analyze chro...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Matloubian, M, Concepcion, R J, Ahmed, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237269/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8056-8063.1994
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