Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3.

Eitemau Tebyg

• Common structural constituents confer I kappa B activity to NF-kappa B p105 and I kappa B/MAD-3.
  gan: Hatada, E N, et al.
  Cyhoeddwyd: (1993)
• Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.
  gan: Mellits, K H, et al.
  Cyhoeddwyd: (1993)
• Human T-cell leukemia virus type I Tax-protein-mediated activation of NF-kappa B from p100 (NF-kappa B2)-inhibited cytoplasmic reservoirs.
  gan: Kanno, T, et al.
  Cyhoeddwyd: (1994)
• The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B.
  gan: Naumann, M, et al.
  Cyhoeddwyd: (1993)
• Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex.
  gan: Li, S, et al.
  Cyhoeddwyd: (1993)