Glycosyl-phosphatidylinositol-anchored and transmembrane forms of CD46 display similar measles virus receptor properties: virus binding, fusion, and replication; down-regulation by hemagglutinin; and virus uptake and endocytosis for antigen presentation by major histocompatibility complex class II molecules.

The CD46 molecule is a receptor for measles virus (MV), CD46, which protects autologous cells from complement-mediated damage, exists in several isoforms which are variably expressed in different human tissues. These isoforms differ in their cytoplasmic and transmembrane regions and in a small porti...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Varior-Krishnan, G, Trescol-Biémont, M C, Naniche, D, Rabourdin-Combe, C, Gerlier, D
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.7891-7899.1994
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