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Autophosphorylation is required for high kinase activity and efficient transformation ability of proteins encoded by host range alleles of v-src.

pp60v-src is a nonreceptor protein tyrosine kinase that can transform both chicken and rodent fibroblasts. The src homology 2 (SH2) domain of this protein serves a critical role in the regulation of protein tyrosine kinase activity. The host range proteins pp60v-src-L, which contains a deletion of a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Virol
Principais autores: Woods, K M, Verderame, M F
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1994
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7267-7274.1994
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