Autophosphorylation is required for high kinase activity and efficient transformation ability of proteins encoded by host range alleles of v-src.
pp60v-src is a nonreceptor protein tyrosine kinase that can transform both chicken and rodent fibroblasts. The src homology 2 (SH2) domain of this protein serves a critical role in the regulation of protein tyrosine kinase activity. The host range proteins pp60v-src-L, which contains a deletion of a...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1994
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7267-7274.1994 |
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