Selectable retrovirus vectors encoding Friend virus gp55 or erythropoietin induce polycythemia with different phenotypic expression and disease progression.

The Friend spleen focus-forming virus induces a massive expansion of erythroid progenitor cells resulting in polycythemia and splenomegaly. The pathogenic agent is the membrane glycoprotein gp55, encoded by the env gene. Recent evidence indicates that gp55 binds to and activates the erythropoietin (...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ahlers, N, Hunt, N, Just, U, Laker, C, Ostertag, W, Nowock, J
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC237163/
https://ncbi.nlm.nih.gov/pubmed/7933106
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires