Improved self-inactivating retroviral vectors derived from spleen necrosis virus.

Self-inactivating (SIN) retroviral vectors contain a deletion spanning most of the right long terminal repeat's (LTR's) U3 region. Reverse transcription copies this deletion to both LTRs. As a result, there is no transcription from the 5' LTR, preventing further replication. Many previously develope...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Olson, P, Nelson, S, Dornburg, R
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1994
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7060-7066.1994
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