Moloney murine leukemia virus-derived retroviral vectors decay intracellularly with a half-life in the range of 5.5 to 7.5 hours.

Replication-incompetent recombinant retroviruses are currently used for gene delivery. The limited efficiency of gene transfer using these vectors hampers implementation of gene therapy. Successful integration of Moloney murine leukemia virus (MMuLV)-derived retroviral vectors into the host cell DNA...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Andreadis, S T, Brott, D, Fuller, A O, Palsson, B O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192101/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311834/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7541-7548.1997
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