Neutralization of primary human immunodeficiency virus type 1 isolates by the broadly reactive anti-V3 monoclonal antibody, 447-52D.

Human monoclonal antibody 447-52D binds to the V3 determinant of the human immunodeficiency virus type 1 (HIV-1) gp120 external glycoprotein. Its binding requires the expression of the GPxR sequence at the center of the V3 domain. HIV-1 variants that are adapted to replication in T-lymphoid cell lin...

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Vydáno v:J Virol
Hlavní autoři: Conley, A J, Gorny, M K, Kessler, J A, Boots, L J, Ossorio-Castro, M, Koenig, S, Lineberger, D W, Emini, E A, Williams, C, Zolla-Pazner, S
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.6994-7000.1994
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