Human herpesvirus 6B origin: sequence diversity, requirement for two binding sites for origin-binding protein, and enhanced replication from origin multimers.

A previously identified human herpesvirus 6B (HHV-6B) origin of DNA replication contains two binding sites for the origin-binding protein (OBPH6B). We have investigated the functional significance of these sites by determining the replication efficiencies of mutated origin sequences, using a transie...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Dewhurst, S, Krenitsky, D M, Dykes, C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8084018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.10.6799-6803.1994
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