The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency.

Eitemau Tebyg

• Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication.
  gan: Kaplan, A H, et al.
  Cyhoeddwyd: (1996)
• Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease.
  gan: Kaplan, A H, et al.
  Cyhoeddwyd: (1994)
• Active human immunodeficiency virus protease is required for viral infectivity.
  gan: Kohl, N E, et al.
  Cyhoeddwyd: (1988)
• Initial Cleavage of the Human Immunodeficiency Virus Type 1 GagPol Precursor by Its Activated Protease Occurs by an Intramolecular Mechanism
  gan: Pettit, Steven C., et al.
  Cyhoeddwyd: (2004)
• Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates
  gan: Pettit, Steve C, et al.
  Cyhoeddwyd: (2005)