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In murine AIDS, B cells are early targets of defective virus and are required for efficient infection and expression of defective virus in T cells and macrophages.

Previous studies showed that B cells and CD4+ T cells are required for induction of a murine retrovirus-induced immunodeficiency syndrome, murine AIDS. Using B6 mice deficient in mature B cells as a result of a knockout of the transmembrane exon of the immunoglobulin M gene, we found that spleen and...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Kim, W K, Tang, Y, Kenny, J J, Longo, D L, Morse, H C
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8084011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.10.6767-6769.1994
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