In murine AIDS, B cells are early targets of defective virus and are required for efficient infection and expression of defective virus in T cells and macrophages.

Previous studies showed that B cells and CD4+ T cells are required for induction of a murine retrovirus-induced immunodeficiency syndrome, murine AIDS. Using B6 mice deficient in mature B cells as a result of a knockout of the transmembrane exon of the immunoglobulin M gene, we found that spleen and...

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Pubblicato in:	J Virol
Autori principali:	Kim, W K, Tang, Y, Kenny, J J, Longo, D L, Morse, H C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8084011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.10.6767-6769.1994
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