Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes.
Hepadnaviruses cause persistent noncytopathic infections of hepatocytes in humans and other animals. Virus replication depends on the pool of viral covalently closed circular DNA (cccDNA) molecules, which serve as transcriptional templates in the nuclei of infected cells. The size of this pool of cc...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1994
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5706-5713.1994 |
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