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Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes.

Hepadnaviruses cause persistent noncytopathic infections of hepatocytes in humans and other animals. Virus replication depends on the pool of viral covalently closed circular DNA (cccDNA) molecules, which serve as transcriptional templates in the nuclei of infected cells. The size of this pool of cc...

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Bibliografske podrobnosti
Main Authors: Lenhoff, R J, Summers, J
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC236973/
https://ncbi.nlm.nih.gov/pubmed/8057452
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