The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.

Functional p53 protein is associated with the ability of cells to arrest in G1 after DNA damage. The E6 protein of cancer-associated human papillomavirus type 16 (HPV-16) binds to p53 and targets its degradation through the ubiquitin pathway. To determine whether the ability of E6 to interact with p...

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Wedi'i Gadw mewn:

Manylion Llyfryddiaeth
Cyhoeddwyd yn:	J Virol
Prif Awduron:	Foster, S A, Demers, G W, Etscheid, B G, Galloway, D A
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1994
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236972/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057451/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5698-5705.1994
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest.

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