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Lack of correlation between basal expression levels and susceptibility to transcriptional shutdown among single-gene murine leukemia virus vector proviruses.

Integrated retroviruses or retroviral vectors may be transcriptionally inactive although their promoter-enhancer regions are able to direct transcription in the host cell. We have used single-gene retroviral vectors with a long terminal repeat-directed neo marker gene to determine if the level of tr...

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Publicat a:J Virol
Autors principals: Duch, M, Paludan, K, Jørgensen, P, Pedersen, F S
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057440/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5596-5601.1994
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