Complementation of a primer binding site-impaired murine leukemia virus-derived retroviral vector by a genetically engineered tRNA-like primer.

Reverse transcription of retroviral genomes is primed by a tRNA annealed to an 18-nucleotide primer binding site. Here, we present a primer complementation system to study molecular interaction of the replication machinery with the primer and primer binding site in vivo. Introduction of eight base s...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Lund, A H, Duch, M, Lovmand, J, Jørgensen, P, Pedersen, F S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1191-1195.1997
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