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A furin-defective cell line is able to process correctly the gp160 of human immunodeficiency virus type 1.

Furin, a subtilisin-like mammalian endoprotease, is thought to be responsible for the processing of many proprotein precursors of cellular and viral origin, including gp160 of human immunodeficiency virus type 1, which share the consensus processing site motif, Arg-X-Lys/Arg-Arg, for protease recogn...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Ohnishi, Y, Shioda, T, Nakayama, K, Iwata, S, Gotoh, B, Hamaguchi, M, Nagai, Y
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8189547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.6.4075-4079.1994
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