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Calcineurin-Dependent Mitochondrial Disturbances in Calcium-Induced Apoptosis of Human Immunodeficiency Virus gp160-Expressing CD4(+) Cells
In CD4(+) UE160 cells with inducible expression of gp160, mechanisms of apoptosis induced by human immunodeficiency virus (HIV) Env protein were analyzed. Induction of gp160 caused intracellular calcium increase followed by the release of cytochrome c from mitochondria, which was inhibited by calcin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135701/ https://ncbi.nlm.nih.gov/pubmed/11739707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.416-420.2002 |
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