Calcineurin-Dependent Mitochondrial Disturbances in Calcium-Induced Apoptosis of Human Immunodeficiency Virus gp160-Expressing CD4(+) Cells

In CD4(+) UE160 cells with inducible expression of gp160, mechanisms of apoptosis induced by human immunodeficiency virus (HIV) Env protein were analyzed. Induction of gp160 caused intracellular calcium increase followed by the release of cytochrome c from mitochondria, which was inhibited by calcin...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Sasaki, Masafumi, Miyazaki, Kozo, Koga, Yasuhiro, Kimura, Genki, Nomoto, Kikuo, Yoshida, Hiroki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.416-420.2002
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