Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins.
The proteolytic cleavages at the NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B junctions of hepatitis C virus (HCV) polyprotein are effected by the virus-encoded serine protease contained within NS3. Using transient expression in HeLa cells of cDNA fragments that code for regions of the HCV polyprot...
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| 出版年: | J Virol |
|---|---|
| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1994
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8189513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.6.3753-3760.1994 |
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