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The "V3" domain is a determinant of simian immunodeficiency virus cell tropism.

Thirty-one different mutant forms of simian immunodeficiency virus (SIVmac) were created with changes in the region of env corresponding to the V3 domain of HIV-1. Sixteen of these mutants had one amino acid change, 12 had two changes, two had three changes, and one had four changes in the SIVmac &q...

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Autors principals: Kirchhoff, F, Mori, K, Desrosiers, R C
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC236873/
https://ncbi.nlm.nih.gov/pubmed/8189506
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