PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1

To better understand DNA recognition and transcription activity by SATB1, the T-lineage-enriched chromatin organizer and transcription factor, we have determined its optimal DNA-binding sequence by random oligonucleotide selection. The consensus SATB1-binding sequence (CSBS) comprises a palindromic...

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Autores principales: Purbey, Prabhat Kumar, Singh, Sunita, Kumar, P. Pavan, Mehta, Sameet, Ganesh, K. N., Mitra, Debashis, Galande, Sanjeev
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367706/
https://ncbi.nlm.nih.gov/pubmed/18187506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1151
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