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Incorporating prior biological information in linkage studies increases power and limits multiple testing

We used the Genetic Analysis Workshop 15 Problem 1 data set to search for expression phenotype quantitative trait loci in a highly selected group of genes with a supposedly correlated role in the development of the enteric nervous system. Our strategy was to reduce the level of multiple testing by a...

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Detalhes bibliográficos
Main Authors: Lantieri, Francesca, Rydbeck, Halfdan, Griseri, Paola, Ceccherini, Isabella, Devoto, Marcella
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367562/
https://ncbi.nlm.nih.gov/pubmed/18466592
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