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Incorporating Prior Biologic Information for High Dimensional Rare Variant Association Studies

BACKGROUND: Given the increasing scale of rare variant association studies, we introduce a method for high-dimensional studies that integrates multiple sources of data as well as allows for multiple region-specific risk indices. METHODS: Our method builds upon the previous Bayesian risk index (BRI)...

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Bibliografiset tiedot
Päätekijät: Quintana, Melanie A., Schumacher, Fredrick R., Casey, Graham, Bernstein, Jonine L., Li, Li, Conti, David V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058572/
https://ncbi.nlm.nih.gov/pubmed/23594496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346021
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