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Incorporating Prior Biologic Information for High Dimensional Rare Variant Association Studies
BACKGROUND: Given the increasing scale of rare variant association studies, we introduce a method for high-dimensional studies that integrates multiple sources of data as well as allows for multiple region-specific risk indices. METHODS: Our method builds upon the previous Bayesian risk index (BRI)...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058572/ https://ncbi.nlm.nih.gov/pubmed/23594496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346021 |
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