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Case-control studies with affected sibships

Related cases may be included in case-control association studies if correlations between related individuals due to identity-by-descent (IBD) sharing are taken into account. We derived a framework to test for association in a case-control design including affected sibships and unrelated controls. F...

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Detalhes bibliográficos
Main Authors: Köhler, Karola, Sohns, Melanie, Bickeböller, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367527/
https://ncbi.nlm.nih.gov/pubmed/18466526
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