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Exploiting gene × gene interaction in linkage analysis

When two genes interact to cause a clinically important phenotype, it would seem reasonable to expect that we could leverage genotypic information at one of the loci in order to improve our ability to detect the other. We were therefore interested in extending the posterior probability of linkage (P...

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Autori principali: Huang, Yungui, Bartlett, Christopher W, Segre, Alberto M, O'Connell, Jeffrey R, Mangin, LaVonne, Vieland, Veronica J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367485/
https://ncbi.nlm.nih.gov/pubmed/18466565
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