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Exploiting gene × gene interaction in linkage analysis

When two genes interact to cause a clinically important phenotype, it would seem reasonable to expect that we could leverage genotypic information at one of the loci in order to improve our ability to detect the other. We were therefore interested in extending the posterior probability of linkage (P...

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Detalhes bibliográficos
Main Authors: Huang, Yungui, Bartlett, Christopher W, Segre, Alberto M, O'Connell, Jeffrey R, Mangin, LaVonne, Vieland, Veronica J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367485/
https://ncbi.nlm.nih.gov/pubmed/18466565
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