Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus.

Simian immunodeficiency virus (SIV) exists within tissues of infected macaques as a mixture of diverse genotypes. The goal of this study was to investigate the biologic significance of this variation in terms of cellular tropism and pathogenicity. PCR was used to amplify and clone 3'-half genom...

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Detalhes bibliográficos
Main Authors: Hirsch, V M, Martin, J E, Dapolito, G, Elkins, W R, London, W T, Goldstein, S, Johnson, P R
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236742/
https://ncbi.nlm.nih.gov/pubmed/8139042
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