Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus.

Simian immunodeficiency virus (SIV) exists within tissues of infected macaques as a mixture of diverse genotypes. The goal of this study was to investigate the biologic significance of this variation in terms of cellular tropism and pathogenicity. PCR was used to amplify and clone 3'-half genom...

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Hlavní autoři: Hirsch, V M, Martin, J E, Dapolito, G, Elkins, W R, London, W T, Goldstein, S, Johnson, P R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC236742/
https://ncbi.nlm.nih.gov/pubmed/8139042
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