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Characterization of impurities in the bulk drug lisinopril by liquid chromatography/ion trap spectrometry

Two trace impurities in the bulk drug lisinopril were detected by means of high-performance liquid chromatography coupled with mass spectrometry (HPLC/MS) with a simple and sensitive method suitable for HPLC/MS(n) analysis. The fragmentation behavior of lisinopril and the impurities was investigated...

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Main Authors: Zhu, Pei-xi, Wang, Dan-hua, Sun, Cui-rong, Shen, Zhi-quan
格式: Artigo
語言:Inglês
出版: Zhejiang University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367377/
https://ncbi.nlm.nih.gov/pubmed/18500778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B0820031
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