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Proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure which can be targeted by G-quadruplex-interactive agents

Previous studies on the functional analysis of the human vascular endothelial growth factor (VEGF) promoter using the full-length VEGF promoter reporter revealed that the proximal 36-bp region (−85 to −50 relative to transcription initiation site) is essential for basal or inducible VEGF promoter ac...

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Detalhes bibliográficos
Main Authors: Sun, Daekyu, Liu, Wei-Jun, Guo, Kexiao, Rusche, Jadrian J., Ebbinghaus, Scot, Gokhale, Vijay, Hurley, Laurence H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367258/
https://ncbi.nlm.nih.gov/pubmed/18413801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2119
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