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Fast In Silico Protein Folding by Introduction of Alternating Hydrogen Bond Potentials

We accelerate protein folding in all-atom molecular dynamics simulations by introducing alternating hydrogen bond potentials as a supplement to the force field. The alternating hydrogen bond potentials result in accelerated hydrogen bond reordering, which leads to rapid formation of secondary struct...

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Autori principali: Wolf, M. G., de Leeuw, S. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367207/
https://ncbi.nlm.nih.gov/pubmed/18434590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.122192
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