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Differential pathogenesis of cowpox virus intranasal infections in mice induced by low and high inoculum volumes and effects of cidofovir treatment

The causes of death from intranasal cowpox virus infections in mice remain unclear. Hypotheses include severe pneumonitis, hepatitis, and/or hyperproduction of cytokines and chemokines. This work explores these hypotheses by studying the influence of low and high volume virus inoculums on viral path...

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Detalhes bibliográficos
Main Authors: Smee, Donald F., Gowen, Brian B., Wandersee, Miles K., Wong, Min-Hui, Skirpstunas, Ramona T., Baldwin, Thomas J., Hoopes, Justin D., Sidwell, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367113/
https://ncbi.nlm.nih.gov/pubmed/18206353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2007.11.013
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