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Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus

N-methanocarbathymidine [(N)-MCT] is a newly identified inhibitor of orthopoxvirus replication in cell culture and in mice. Limited published animal studies indicated the compound is effective by intraperitoneal (i.p.) route at 10-100 mg/kg/day. More extensive studies using different treatment regim...

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Detalhes bibliográficos
Main Authors: Smee, Donald F., Hurst, Brett L., Wong, Min-Hui, Glazer, Robert I., Rahman, Aquilur, Sidwell, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268765/
https://ncbi.nlm.nih.gov/pubmed/17658623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2007.06.005
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