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Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate
When Saccharomyces cerevisiae cells are starved of inorganic phosphate, the Pho80-Pho85 cyclin–cyclin-dependent kinase (CDK) is inactivated by the Pho81 CDK inhibitor (CKI). The regulation of Pho80-Pho85 is distinct from previously characterized mechanisms of CDK regulation: the Pho81 CKI is constit...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367112/ https://ncbi.nlm.nih.gov/pubmed/18059263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2007.52 |
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