Overexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver

Various drugs such as phenobarbital (PB) trigger translocation of constitutive active/adrostane receptor (CAR) from the cytoplasm into the nucleus of mouse liver cells without directly binding to the receptor. We have now characterized the guanine nucleotide exchange factor epithelial cell-transform...

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Bibliografiset tiedot
Päätekijät: Hosseinpour, Fardin, Timsit, Yoav, Koike, Chika, Matsui, Kenji, Yamamoto, Yukio, Moore, Rick, Negishi, Masahiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367110/
https://ncbi.nlm.nih.gov/pubmed/17904126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.09.024
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